This is the story of how we produced the first brain map of mitochondria—or the human brain bioenergetic landscape. The paper was published in the journal Nature.
Incredible work bridging cellular bioenergetics with whole-brain imaging. The way this team aligned mitochondiral data to MNI space is kinda genius since it lets any neuroimaging study tap into these metabolic patterns. I remeber struggling with similar cross-scale issues in my own lab work. Linking subcellular machinery to macroscale brain activity could actually reshape how we interpret fMRI energy signals.
Incredible work bridging cellular bioenergetics with whole-brain imaging. The way this team aligned mitochondiral data to MNI space is kinda genius since it lets any neuroimaging study tap into these metabolic patterns. I remeber struggling with similar cross-scale issues in my own lab work. Linking subcellular machinery to macroscale brain activity could actually reshape how we interpret fMRI energy signals.
If this works and we can qualify mitochondria biology with magnetic resonance signals alone that would be amazing. Early data is promising.